Gonadotropin-Releasing Hormone Pulse Sensitivity of Follicle-Stimulating Hormone- Gene Is Mediated by Differential Expression of Positive Regulatory Activator Protein 1 Factors and Corepressors SKIL and TGIF1
نویسندگان
چکیده
Medical Research Service (D.S.M., R.T., M.F., S.S., N.J.G.W.), Veterans Affairs San Diego Healthcare System, San Diego, California 92161; and the Biomedical Sciences (D.S.M., M.A.L., N.J.G.W.) and Interfaces (D.S.M.) Graduate Programs and Departments of Reproductive Medicine (S.A.C., M.A.L.) and Medicine (D.S.M., R.T., M.F., S.S., N.J.G.W.), University of California, San Diego, San Diego, California 92093
منابع مشابه
Cloning and expression of Iranian Turkmen-thoroughbred horse follicle stimulating hormone in Pichia pastoris
Background: Follicle stimulating hormone (FSH) plays an essential role in reproductive physiology and follicular development. Objective: A new variant of the equine fsh (efsh) gene was cloned, sequenced, and expressed in Pichia pastoris (P. pastoris) GS115 yeast expression system. Materials and Methods: The full-length cDNAs of the efshα and efshβ chains were amplified by reverse transcriptio...
متن کاملP-198: Utilization of Pichia Pastoris Secretion System for Expression of Equine Follicle Stimulating Hormone
Background: Equine follicle stimulating hormone (eFSH) is a pituitary heterodimeric glycoprotein consists of noncovalently linked of generic alpha subunit and a hormone specific beta subunit. The molecular weights of the subunits are similar and about 16 KD. In general, FSH plays a key role in controlling vertebrate gonadal functions. In female mammals, ovarian maturation and follicular growth ...
متن کاملP-197: Expression of Bovine Follicle Stimulating Hormone Subunits in Pichia Pastoris
Background: Bovine follicle stimulating hormone (bFSH) belongs to the family of glycoprotein hormones that are released from the pituitary gland or the placenta. This hormone is a heterodimer consisting of common α- and specific β-subunit. Bovine FSH is used for reproductive technology such as superovulation in farm animals and polycystic ovary syndrome treatment. Also this hormone is produced ...
متن کاملP-98: The Effect of Primary pH Values of Medium Culture on Expression of Human Follicle Stimulating Hormone in Recombinant Chinese Hamster Ovary Cells.
Background One of the common gonadotropin hormones used for infertility treatment is recombinant Follicle stimulating hormone (rFSH). pH is an environmental factor that can affect production of recombinant proteins with no imposing cost. Culture pH is known as a parameter that significantly affects cell growth and protein production. In this study, tried to investigate the effect of different p...
متن کاملP-132: The Effect of Different Fetal Bovine Serum Levels on Recombinant Chinese Hamster Ovary Cells, Expressing HumanFollicle Stimulating Hormone
Background: Follicle stimulating hormone (FSH) is one of the most common and effective gonadotropin hormones used in infertility treatment. Production of FSH as a drug is affordable as long as it is done with minimal cost. FBS is the most expensive component in medium culture furthermore; it’s being controversial to cause unnecessary suffering for the unborn calf for collection their serum. In ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2011